Lycia Therapeutics

Vice President (VP) / Senior VP, Clinical Development

South San Francisco Full-time On-site
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Job Description

Lycia Therapeutics is a biotechnology company using its proprietary lysosomal targeting chimera (LYTAC) platform to discover and develop best-in-class therapeutics that degrade extracellular and membrane-bound proteins. These proteins drive a wide range of difficult-to-treat diseases, including autoimmune and inflammatory conditions. Lycia was established in 2019 in collaboration with academic founder and Nobel Laureate Carolyn Bertozzi, Ph.D., professor of chemistry and HHMI investigator at Stanford University. In June, 2026, Lycia Therapeutics completed a $75 million Series D financing to advance its pipeline of LYTAC extracellular protein degraders into the clinic. Lycia is headquartered in South San Francisco. Visit https://lyciatx.com/ for more information. Position Summary

Lycia is seeking a highly motivated, innovative, and collaborative clinical development leader to join our team in advancing our pipeline of LYTAC degraders and help establish Lycia as the industry leader in endosomal-lysosomal degradation and delivery. The successful candidate is expected to have a strong drug development track record of advancing programs from early through mid- and late-phase clinical development.

The candidate will be expected to drive the study design, study implementation, data analysis, safety monitoring of mid- and late-phase clinical trials in close partnership with early phase / translational development group and the research organization. The successful candidate will be instrumental in providing medical leadership and expertise to help guide the direction and actively support the advancement of our pipeline.

The candidate will have a strong background in medicine, recognized expertise in their therapeutic area and strong leadership abilities, and a passion for driving innovation and excellence in a start-up biotech company. The role will report to the Chief Medical Officer.

Frequently Asked Questions

What does the Vice President (VP) / Senior VP, Clinical Development role at Lycia Therapeutics involve?

The Vice President (VP) / Senior VP, Clinical Development position at Lycia Therapeutics in South San Francisco is a full-time role. Lycia Therapeutics is a biotechnology company using its proprietary lysosomal targeting chimera (LYTAC) platform to discover and develop best-in-class therapeutics that degrade extracellular and membrane-bound proteins. These proteins drive a wide range of difficult-to-treat diseases, including autoimmune and inflammatory conditions. Lycia was established in 2019 in collaboration with academic founder and Nobel Laureate Carolyn Bertozzi, Ph.D., professor of chemistry and HHMI investigator at Stanford University. In June, 2026, Lycia Therapeutics completed a $75 million Series D financing to advance its pipeline of LYTAC extracellular protein degraders into the clinic. Lycia is headquartered in South San Francisco. Visit https://lyciatx.com/ for more information.

What skills are required for Vice President (VP) / Senior VP, Clinical Development at Lycia Therapeutics?

Please refer to the full job description for required skills and qualifications.

What is the salary for Vice President (VP) / Senior VP, Clinical Development at Lycia Therapeutics?

The salary for this position is not publicly listed. You can negotiate during the interview process. Check Glassdoor or Levels.fyi for estimates.

Is the Vice President (VP) / Senior VP, Clinical Development position at Lycia Therapeutics remote or on-site?

This position is On-site. The role is based in South San Francisco.

How do I apply for Vice President (VP) / Senior VP, Clinical Development at Lycia Therapeutics?

You can apply for this position directly through the employer's careers page. Click the 'Apply Now' button on this page to be redirected to the original listing. Make sure your resume is ATS-optimized. Use SpotChange's free ATS test to check.

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About This Role

Vice President (VP) / Senior VP, Clinical Development at Lycia Therapeutics is a full-time other position in South San Francisco. Education: Doctorate preferred. Experience: 5+ years.

This role is classified as on-site and is suitable for senior-level professionals. Ghost Score 20/100 (Probably Active) indicates this listing is probably active with recent employer engagement.

To apply, visit the official application page through the Apply Now button above. SpotChange Jobs provides AI-powered career tools including resume optimization, ATS testing, interview preparation, and salary negotiation assistance.