Mithrl

Member of Technical Staff, Data Engineering

San Francisco FullTime On-site $180/year
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Job Description

ABOUT MITHRL We envision a world where novel drugs and therapies reach patients in months, not years, accelerating breakthroughs that save lives. Mithrl is building the world’s first commercially available AI Co-Scientist—a discovery engine that empowers life science teams to go from messy biological data to novel insights in minutes. Scientists ask questions in natural language, and Mithrl answers with real analysis, novel targets, and patent-ready reports. Our traction speaks for itself: - 12X year-over-year revenue growth - Trusted by leading biotechs and big pharma across three continents - Driving real breakthroughs from target discovery to patient outcomes. WHAT YOU WILL DO Build and own an AI-powered ingestion & normalization pipeline to import data from a wide variety of sources — unprocessed Excel/CSV uploads, lab and instrument exports, as well as processed data from internal pipelines. Develop robust schema mapping, coercion, and conversion logic (think: units normalization, metadata standardization, variable-name harmonization, vendor-instrument quirks, plate-reader formats, reference-genome or annotation updates, batch-effect correction, etc.). Use LLM-driven and classical data-engineering tools to structure “semi-structured” or messy tabular data — extracting metadata, inferring column roles/types, cleaning free-text headers, fixing inconsistencies, and preparing final clean datasets. Ensure all transformations that should only happen once (normalization, coercion, batch-correction) execute during ingestion — so downstream analytics / the AI “Co-Scientist” always works with clean, canonical data. Build validation, verification, and quality-control layers to catch ambiguous, inconsistent, or corrupt data before it enters the platform. Collaborate with product teams, data science / bioinformatics colleagues, and infrastructure engineers to define and enforce data standards, and ensure pipeline outputs integrate cleanly into downstream analysis and storage systems. WHAT YOU BRING Must-have - 5+ years of experience in data engineering / data wrangling with real-world tabular or semi-structured data. - Strong fluency in Python, and data processing tools (Pandas, Polars, PyArrow, or similar). - Excellent experience dealing with messy Excel / CSV / spreadsheet-style data — inconsistent headers, multiple sheets, mixed formats, free-text fields — and normalizing it into clean structures. - Comfort designing and maintaining robust ETL/ELT pipelines, ideally for scientific or lab-derived data. - Ability to combine classical data engineering with LLM-powered data normalization / metadata extraction / cleaning. - Strong desire and ability to own the ingestion & normalization layer end-to-end — from raw upload → final clean dataset — with an eye for maintainability, reproducibility, and scalability. - Good communication skills; able to collaborate across teams (product, bioinformatics, infra) and translate real-world messy data problems into robust engineering solutions. Nice-to-have - Familiarity with scientific data types and “modalities” (e.g. plate-readers, genomics metadata, time-series, batch-info, instrumentation outputs). - Experience with workflow orchestration tools (e.g. Nextflow, Prefect, Airflow, Dagster), or building pipeline abstractions. - Experience with cloud infrastructure and data storage (AWS S3, data lakes/warehouses, database schemas) to support multi-tenant ingestion. - Past exposure to LLM-based data transformation or cleansing agents — building or integrating tools that clean or structure messy data automatically. - Any background in computational biology / lab-data / bioinformatics is a bonus — though not required. WHAT YOU WILL LOVE AT MITHRL - Mission-driven impact: you’ll be the gatekeeper of data quality — ensuring that all scientific data entering Mithrl becomes clean, consistent, and analysis-ready. You’ll have outsized influence over the reliability and trustworthiness of our entire data + AI stack. - High ownership & autonomy: this role is yours to shape. You decide how ingestion works, define the standards, build the pipelines. You’ll work closely with our product, data science, and infrastructure teams — shaping how data is ingested, stored, and exposed to end users or AI agents. - Team: Join a tight-knit, talent-dense team of engineers, scientists, and builders - Culture: We value consistency, clarity, and hard work. We solve hard problems through focused daily execution - Speed: We ship fast (2x/week) and improve continuously based on real user feedback - Location: Beautiful SF office with a high-energy, in-person culture - Benefits: Comprehensive PPO health coverage through Anthem (medical, dental, and vision) + 401(k) with top-tier plans We encourage you to apply even if you do not believe you meet every single qualification. Not all strong candidates will meet every single qualification as listed. Research shows that people who identify as being from underrepresented groups are more prone to experiencing imposter syndrome and doubting the strength of their candidacy, so we urge you not to exclude yourself prematurely and to submit an application if you're interested in this work. We think AI systems like the ones we're building have enormous social and ethical implications. We think this makes representation even more important, and we strive to include a range of diverse perspectives on our team.

Frequently Asked Questions

What does the Member of Technical Staff, Data Engineering role at Mithrl involve?

The Member of Technical Staff, Data Engineering position at Mithrl in San Francisco is a fulltime role. ABOUT MITHRL We envision a world where novel drugs and therapies reach patients in months, not years, accelerating breakthroughs that save lives. Mithrl is building the world’s first commercially available AI Co-Scientist—a discovery engine that empowers life science teams to go from messy biological data to novel insights in minutes. Scientists ask questions in natural language, and Mithrl answers with real analysis, novel targets, and patent-ready reports. Our traction speaks for itself: - 12X year-over-year revenue growth - Trusted by leading biotechs and big pharma across three continents - Driving real breakthroughs from target discovery to patient outcomes.

What skills are required for Member of Technical Staff, Data Engineering at Mithrl?

Key skills for this role include: Python, GO, Rust, Scala, AWS, S3, RDS, Pandas, Airflow, ETL.

What is the salary for Member of Technical Staff, Data Engineering at Mithrl?

The listed compensation for this role is $180/year. Actual salary may vary based on experience and location.

Is the Member of Technical Staff, Data Engineering position at Mithrl remote or on-site?

This position is On-site. The role is based in San Francisco.

How do I apply for Member of Technical Staff, Data Engineering at Mithrl?

You can apply for this position directly through the employer's careers page. Click the 'Apply Now' button on this page to be redirected to the original listing. Make sure your resume is ATS-optimized. Use SpotChange's free ATS test to check.

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About This Role

Member of Technical Staff, Data Engineering at Mithrl is a fulltime data & analytics position in San Francisco. Key skills include Python, GO, Rust, Scala, AWS, S3, RDS, Pandas. Compensation: $180/year. Education: Master's Degree preferred. Experience: 5+ years.

This role is classified as on-site and is suitable for staff-level professionals. Ghost Score 35/100 (Possibly Stale) indicates this listing is possibly stale — verify on the employer site.

To apply, visit the official application page through the Apply Now button above. SpotChange Jobs provides AI-powered career tools including resume optimization, ATS testing, interview preparation, and salary negotiation assistance.